To request dry ice, please provide the following and email information to ocr@wakehealth.edu. Outcome data from NDSR will include daily estimated energy and nutrient intake, as well as food, food group and dietary supplement data. Learn more about our nondiscrimination policy and services available to you. Known as the Investigation of Serial Studies to Predict Your COVID Therapeutic Response with Biomarker Integration and Adaptive Learning (I-SPY COVID Trial), the study is a collaboration among pharmaceutical industry members of the recently formed COVID Research & Development Alliance and others; the Quantum Leap Healthcare Collaborative, a partnership of medical researchers and investors; and the Food and Drug Administration. First Floor How will my privacy be protected when I participate in the study? Clin Nutr. RESEARCHERS ARE LOOKING TO SEE IF DRUGS APPROVED FOR OTHER USES CAN HELP TREAT CORONAVIRUS IN CRITICALLY ILL PATIENTS. Several drugs have been identified that either neutralize the virus or help heal lungs or other organ injuries that make people severely ill from COVID-19. Fostering collaborative interdisciplinary research into the causes of common human disorders, such as heart disease, diabetes, obesity, and other aging-related morbidities. Assess trial accrual potential and plausible overlap between competing trials. Aiming to improve the lives of people with diabetes, obesity and other metabolic disorders through basic, clinical and translational research. 6:30 am - 4:30 pm Visceral adipose tissue is positively correlated with risk of cardiometabolic syndrome that predisposes to cardiovascular disease and diabetes. Does my insurance cover the cost of being in the study. “By identifying effective treatments in real-time, our goal is to reduce mortality and the length of time patients spend on ventilators,” Thomas added. Our designation by the National Cancer Institute, 1 of only 51 in the U.S., ensures that the Comprehensive Cancer Center is on the forefront of cancer research and breakthrough medicine. Wake Forest Baptist Health does not discriminate on the basis of race, color, national origin, sex, sexual orientation, gender identity, age or disability. Phone: 336-716-1195 | Fax: 336-716-1358 Driving the Wake Forest Baptist vision to become a leading academic learning health system. 2002 Dec 17;106(25):3143-421. 1 Medical Center Boulevard If I want to stop the study, am I allowed to drop out? CRU nurses and clinical research technicians provide patient care support for pediatric and adult research projects. Bertoli S, Leone A, Vignati L, Bedogni G, Martínez-González MÁ, Bes-Rastrollo M, Spadafranca A, Vanzulli A, Battezzati A. Adherence to the Mediterranean diet is inversely associated with visceral abdominal tissue in Caucasian subjects. Feedback, which can be offered anonymously, welcomed. Int Med Rev In press. At Wake Forest Baptist Health, diversity has always been one of our core values. 1 Medical Center Boulevard Winston-Salem, North Carolina, 27157 The goal for the 3 intra-study recalls is to capture intake data for 2 weekdays and 1 weekend day for each participant. Wake Forest School of Medicine Clinical and Translational Sciences Institute, 486 N. Patterson Ave., Winston-Salem, NC 27101. Phone: 336-716-3540. Orders can be placed on an as needed basis or established as a standing weekly, monthly, bi-monthly, etc. Participants in the control group will complete the RAND 20-Item Short Form Survey. Berryman CE, West SG, Fleming JA, Bordi PL, Kris-Etherton PM. In October 2019, Wake Forest Baptist became the first health system in the state to join that trial.In addition to Wake Forest Baptist, the other initial I-SPY COVID Trial sites are Columbia University Medical Center, Montefiore Medical Center, Sanford USD Medical Center, University of Alabama, University of California San Francisco, University of Colorado Denver, University of Pennsylvania, University of Southern California and Yale University. Wake Forest School of Medicine conducts a variety of clinical trials through the BeInvolved program. Providing research infrastructure to this leading health care system that is at the forefront of translating scientific discoveries. Studies a U.S. FDA-regulated Drug Product: Studies a U.S. FDA-regulated Device Product: Visceral adiposity [ Time Frame: Visit 1 (Screening, -2 to 0 weeks) and Visit 8 (26 weeks) ], Hepatic lipid content [ Time Frame: Visit 1 (Screening, -2 to 0 weeks and Visit 8 (26 weeks) ], Metabolic syndrome markers (serum triglycerides, serum cholesterol, fasting serum glucose, fasting insulin) [ Time Frame: Visit 2 (Baseline visit 0 weeks), Visit 5 (12 weeks), Visit 8 (26 weeks) ], High-sensitivity C-reactive protein (hs-CRP) [ Time Frame: Visit 2 (baseline/randomization, Week 0), Visit 5 (12 weeks), Visit 8 (26 weeks) ], Red blood cell (RBC) monounsaturated fat/polyunsaturated fat (MUFA/PUFA) ratio [ Time Frame: Visit 2 (Baseline/Randomization Visit, 0 weeks), Visit 5 (12 weeks), Visit 8 (26 weeks) ], Blood pressure [ Time Frame: Visit 2 (baseline/randomization 0 weeks) Visit 3 (4 weeks), Visit 4 (8 weeks), Visit 5 (12 weeks), Visit 6 (16 weeks), Visit 7 (10 weeks), Visit 8 (26 weeks) ], Weight [ Time Frame: Visit 2 (baseline/randomization), Visit 5 (12 weeks) and Visit 8 (26 weeks-final) ], Waist circumference [ Time Frame: Visit 1 (screening -2 to 0 weeks), Visit 2 (baseline/randomization 0 weeks), Visit 5 (12 weeks), Visit 8 (26 weeks) ], Diet, Food and Avocado Satisfaction [ Time Frame: Visit 2 (baseline/randomization, 0 weeks), Visit 5 (12 weeks), Visit 8 (26 weeks) ], Quality of life RAND 36-Item Short Form Survey Instrument (SF-36) [ Time Frame: Visit 2 (baseline), Visit 5 (12 weeks) and Visit 8 (26 weeks-final) ], Quality of Life RAND 20-Item Short Form Survey (SF-20) [ Time Frame: Visit 3 (4 weeks), Vist 4 (8 weeks) Visit 6 (16 weeks), Visit 7 (20 weeks) ], Sleep quality [ Time Frame: Visit 2 (baseline), Visit 5 (12 weeks) and Visit 8 (26 weeks-final) ], 24-hour diet recall [ Time Frame: Visit 1 (screening, -2 to 0 weeks), Visit 4 (8 weeks), visit 6 (16 weeks), Visit 8 (26 weeks) ], Increased waist circumference defined as ≥35 inches for women, ≥40 inches for men, Not currently eating more than 2 avocados per month (habitual intake in U.S.), Allergies to latex or oral allergy syndrome, Not willing or unable to undergo MRI scans. This clinical trial aims to assess the effect of providing one avocado per day on established parameters of health in comparison with a control group maintaining their habitual diets. sohene@wakehealth.edu But many trials and studies also may require healthy participants. Wake Forest Baptist Health does not discriminate on the basis of race, color, national origin, sex, sexual orientation, gender identity, age or disability. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Wake Forest University Health Sciences: ClinicalTrials.gov Identifier: NCT04039204 Other Study ID Numbers: IRB00059474 : First Posted: July 31, 2019 Key Record Dates: Last Update Posted: July 31, 2020 Last Verified: July 2020 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Avocado consumption by adults is associated with better nutrient intake, diet quality and some measures of adiposity: NHANES Survey, 2001-2012. Phlebotomy is performed after a minimum 8 hour fast. Winston-Salem, North Carolina, 27106 Epub 2007 Mar 23. They will follow a standardized manual of procedures for dietary data collection and dietary data management. 2016 Oct;24(10):2176-84. doi: 10.1002/oby.21589. For general information, Learn About Clinical Studies. You'll also obtain detailed materials explaning how the study will be conducted and information about your involvement and care during the study. Erratum in: Ann Intern Med. Research Core Facilities are important to the research mission for effective and efficient use of: These services are generally purchased on a fee-for-service basis, unless the project is large enough that a percent effort is requested in the grant or contract. Talk with your doctor and family members or friends about deciding to join a study. 1st Floor, Meads Hall Jim Bland Status: Enrolling, Phase I. You will have an opportunity to ask questions about the study and you will be asked to sign a consent form for your participation. 2013 Nov 27;12:155. doi: 10.1186/1475-2891-12-155. Seeking to improve the burden of critical care-related disorders on human health through innovative research. The recalls are collected and analyzed using Nutrition Data System for Research (NDSR) software Vs 2017. Before consenting to participate in the study, you should: Our number one priority is protecting our patients. Working to advance health equity and population health research. Wake Forest School of Medicine will not be liable for any direct, indirect, consequential, special, exemplary, or other damages arising therefrom. Symposia Series Dean's Research Symposia Series - Video series featuring our Wake Forest Baptist Medical Center investigators sharing bold thinking, latest discoveries and their passion to improve health. 1 Medical Center Boulevard Local and national elections & political news, delivered to your inbox. The Wake Forest Clinical and Translational Science Institute (CTSI) has been made possible by a Clinical and Translational Science Award from the National Institutes of Health through its National Center for Advancing Translational Sciences. Non-contrast MRI scans will be performed to assess the volume of visceral adipose tissue. When you join a study, you receive contact information from the researcher leading the study. Create an infrastructure to support and promote appropriate research billing. Driving continuous improvement by translating what we learn into what we do. carlsmit@wakehealth.edu A randomized 3×3 crossover study to evaluate the effect of Hass avocado intake on post-ingestive satiety, glucose and insulin levels, and subsequent energy intake in overweight adults. Randomization is performed automatically by the data entry system using a block design and stratified by site. Targeting the translation of cutting-edge scientific advances to the patient and community at large through team based innovative research. Participants are randomly assigned to one of two equally sized groups. Wake Forest School of Medicine will not be liable for any direct, indirect, consequential, special, exemplary, or other damages arising therefrom. Clinical studies are well planned. Wake Forest School of Medicine conducts a variety of clinical trials through the BeInvolved program. Questions may include: Studies show that those who take part in a clinical trial, on average achieve equal or better health results than those who don't. Epub 2015 Oct 20. Questionnaires include the following: health and demographic including eating habits and physical activity; diet, food and avocado satisfaction (intervention group only); quality of life; and quality of sleep. Subscribe | Weekly Newsletters: The Research Rundown and Funding Opportunities. Each item is scored on a 0 to 100 range so that the lowest and highest possible scores are 0 and 100. A Pilot Trial of Continuous Portable Postoperative Hemodynamic And Saturation Monitoring On Hospital Wards: Results Status Ongoing ACT or pACT? Participants are followed for outcomes for a six-month period. Clinical Trials .  (Clinical Trial). Can my condition get worse by being in the study? Sandra Norona Phone: 336-716-1195 | Fax: 336-716-1358 Paniagua JA, Gallego de la Sacristana A, Romero I, Vidal-Puig A, Latre JM, Sanchez E, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F. Monounsaturated fat-rich diet prevents central body fat distribution and decreases postprandial adiponectin expression induced by a carbohydrate-rich diet in insulin-resistant subjects. Participants are pre-screened over the telephone initially to assess eligibility and likelihood of compliance. This clinical trial aims to assess the effect of providing one avocado per day on established parameters of health in comparison with a control group maintaining their habitual diets. Wake Forest Baptist Health research studies follow strict codes of conduct.